METiS TechBio’s blockbuster IPO signals rising investor interest in AI startups focused on how drugs are delivered inside the body
Updated
May 14, 2026 3:02 PM

HIV-1 virus particles, coloured red. PHOTO: UNSPLASH
Investors are beginning to place bigger bets on AI startups focused on drug delivery infrastructure rather than drug discovery alone. That shift was on display this week after METiS TechBio, a Hong Kong tech-bio startup focused on AI-powered drug delivery systems, debuted on the Hong Kong Stock Exchange.
The listing made METiS TechBio the world’s first publicly traded AI-powered drug delivery startup and the first AI-powered large-molecule biopharmaceutical startup listed in Hong Kong. The startup raised more than HKD 2.1 billion through its IPO, making it the largest healthcare listing in Hong Kong so far in 2026.
Investor demand was unusually strong. The Hong Kong public offering was oversubscribed by more than 6,900 times while the international tranche recorded 82 times oversubscription. More than 280 institutional investors participated in the international placing.
The strong demand reflects a wider shift in AI biotech. Over the past few years, much of the sector’s attention has focused on using AI to discover new drugs or molecules. METiS is taking a different approach. The startup focuses on how medicines are delivered inside the body after they are developed.
That challenge is becoming harder to ignore in biotech. Designing a therapy is only one part of the process. Delivering it precisely to specific organs, tissues or cells remains a major hurdle, especially for newer therapies involving RNA, proteins and large-molecule drugs.
METiS is trying to solve that problem through its proprietary NanoForge platform. The system uses AI to design and test nanodelivery systems that help medicines reach targeted areas inside the body more efficiently. The platform combines AI models, simulation systems and high-throughput screening tools to speed up formulation development and improve delivery precision.
The startup says it has already achieved targeted delivery across eight organs and tissue systems including the liver, lungs, heart, muscles and central nervous system.
One of its lead programs, MTS-004, became China’s first AI-enabled formulation drug to complete a Phase III clinical trial. The drug is being developed for pseudobulbar affect, a neurological condition that affects emotional expression. According to the startup, AI tools helped reduce preclinical formulation development time from up to two years to less than three months.
Investor interest in the IPO also came from some of the world’s largest asset managers and healthcare funds. BlackRock led the cornerstone investments with a USD 50 million subscription. Other participating investors included UBS Asset Management Singapore, Mirae Asset, ORIX Corporation, Deerfield, RTW, Hillhouse Capital and IDG Capital.
METiS is also building what it describes as a “platform collaboration + product partnership” business model. The startup currently works with more than 30 pharmaceutical and biotechnology partners globally, including large pharmaceutical companies and medical research institutions.
The company reported RMB 105 million in revenue in 2025, largely tied to upfront payments connected to its MTS-004 partnership agreements. It also said some platform collaboration contracts could reach milestone values of up to USD 109 million.
Chris Lai said: "The future of biomedicine will no longer be simply about 'taking medicine when one falls ill.' METiS TechBio's ambition is to harness AI to build nano-rockets that can navigate with precision through the inner space of the human body's 30 trillion cells, write the code of nucleic acids and proteins into cells, and reprogram diseased and aging cells into healthy cells. This was our founding aspiration, and it is the mission to which we will dedicate our lives. The IPO marks a new starting point for us to accelerate forward, and we will strive to live up to the support and trust we have received from all sectors."
The IPO also highlights how Hong Kong is increasingly positioning itself as a hub for next-generation biotech and AI healthcare startups. While investor excitement around AI drug discovery has cooled in parts of the market, startups focused on delivery systems and biotech infrastructure are beginning to attract stronger institutional backing.
For METiS, the challenge now will be turning that investor confidence into commercially viable therapies and long-term partnerships. But the listing suggests that AI-driven drug delivery is starting to emerge as a category investors are willing to treat as core biotech infrastructure rather than a niche research experiment.
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Skip the slogans—real Women’s Day campaigns create impact that lasts
Updated
April 1, 2026 8:56 AM

Mother Armenia monument in Victory Park, Gyumri city, Armenia. PHOTO: ADOBE STOCK
Women’s Day offers brands an opportunity to show what they stand for through meaningful action. But the strongest International Women’s Day campaigns do more than say “thank you”. They speak to women’s everyday lives.
Instead of big, vague empowerment slogans, some brands focus on small moments that shape confidence and wellbeing. Think about how we compliment young girls, how safe public spaces feel, what comfort really looks like and how friendship plays help women grow. When a campaign is built on a real insight and backed by something practical, it lands harder and lasts longer.
If you’re a startup planning a Women’s Day initiative, there’s value in studying what actually works. The examples below show how clarity, credibility and usefulness can turn International Women’s Day into something that feels meaningful and on-brand.

To celebrate the International Day of the Girl on October 11, 2025, Dove launched #ChangeTheCompliment—a campaign that asked parents and caregivers to rethink how they praise girls. Instead of defaulting to looks-based comments, Dove encouraged adults to acknowledge qualities like resilience, intelligence and determination alongside beauty.
The idea was grounded in data from Dove’s 2024 Real State of Beauty report, which found that more than 60% of girls feel pressure to be beautiful. Dove brought the message to life through a digital film showing parents broadening their praise in everyday moments.
In Canada, the campaign expanded through a partnership with psychologist Dr. Vanessa Lapointe, who helped anchor #ChangeTheCompliment in expert insight. She linked the campaign’s core message to Dove’s long-running Self-Esteem Project, launched in 2004 to provide free, evidence-based tools developed with psychologists and body image experts. Some of these tools included “Confident Me”, a classroom workshop on body confidence and “Amazing Me”, age-appropriate lessons designed to support self-esteem at school.
What worked here is that it didn’t stay inside a brand video. Parents, teachers and creators joined in by sharing their own examples online, posting revised compliments, building quick classroom activities or filming short clips where they swapped appearance-based praise for character-based words. From social posts to simple at-home conversations, the idea travelled beyond the original film and made participation easy.
Startup takeaway: Don’t build a Women’s Day campaign around a fuzzy theme. Focus on specific, everyday behaviors your audience relates to and design your campaign to shift them. Specificity makes your message practical and memorable.

In March 2024, Tetley Green Tea Immune launched the “I Am More Than My Nickname” campaign in India to challenge a common social habit: labeling someone’s fitness based on how their body looks. In many communities, body-type nicknames are used casually. Some of them might sound harmless, but they can chip away at confidence and self-worth over time. Tetley’s point was simple: fitness isn’t a body size. It’s strength, health and well-being.
The campaign centered on a digital film featuring a young girl nicknamed “Golu”, a Hindi term often used to describe someone as chubby. Throughout the film, she’s judged before she even tries, with people deciding what she can and cannot do based on her appearance. As the story unfolds, she pushes back. The film closes with women of different body types holding placards displaying various nicknames, ending with a clear line: “My Body Can, Your Body Can, Every Body Can”. It’s a strong example of a brand taking a familiar social habit and giving people a new way to see it.
Startup takeaway: Look for one small, common behaviour your audience sees every day. Then give people a simple way to engage with it, whether that’s sharing a story, rethinking a phrase or calling out a habit. When participation is baked into the idea, the campaign spreads naturally.

For International Anti-Street Harassment Week 2025, L'Oréal Paris launched its “Never Your Fault” campaign as part of its Stand Up Against Street Harassment program. The campaign drew on L’Oréal Paris research with Ipsos showing the scale of the problem: 75% of women reported experiencing harassment, and 60% said they adjust their clothing or appearance in public.
The message was clear: harassment is never the victim’s fault, and public spaces should feel safer for women. That matters because a lot of women still end up internalizing blame and changing how they dress just to lower the risk.
The campaign also came with a clear next step. It builds on L’Oréal’s partnership with Right To Be, an international NGO focused on stopping harassment, which began in 2020. Through Right To Be’s 5D framework—Distract, Delegate, Document, Delay and Direct—the program teaches bystanders simple, practical ways to intervene safely in the moment.
Startup takeaway: If you’re addressing a sensitive issue in a Women’s Day campaign, don’t go about it alone. Work with experts who bring trust, depth and real tools. It makes your message stronger fast.
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In 2025, Van Heusen Innerwear marked Women’s Day with a single visual that many women immediately recognized. The poster showed a crumpled shirt with a bra placed over it, capturing that end-of-day moment of relief.
The slogan on the poster—“Happy Women’s Day has nothing to do with us”—makes the point that real comfort is personal, not performative. The message wasn’t really about taking off a bra, but about the pressure women carry all day, including the expectation to look a certain way, feel a certain way and still keep going. By leaning into a real, everyday experience, Van Heusen positioned itself as a brand that listens rather than lectures.
Startup takeaway: Skip the predictable in Women’s Day slogans. Find an honest, lived moment and build around it. When your campaign reflects real life, it feels relevant instead of seasonal.

In 2025, Mattel celebrated International Women’s Day by honoring real-life female friendship duos with one-of-a-kind Barbie Role Model dolls made in their likeness. The campaign focused on the idea that strong friendships help women grow, succeed and support each other. Instead of spotlighting individual achievement, it highlighted collective strength—women empowering women.
By featuring duos such as Alicia Keys and Ann Mincieli, Jordan Chiles and Jade Carey and other global pairs across sports, entertainment and advocacy, the campaign framed friendship as a source of confidence and ambition from girlhood onward. To make it practical, Mattel partnered with psychologist and best-selling author Dr. Marisa G. Franco, who shared simple advice for girls: take initiative in making friends, assume people will like you, express appreciation openly, try new activities together and prioritize quality over quantity in relationships.
Startup takeaway: If your Women’s Day campaign is built on a social insight, make it actionable. Storytelling helps, but tools, education and frameworks are what make it useful.
Across these International Women’s Day campaigns, the playbook is consistent: choose one real, everyday behaviour and shift it. Whether it’s the way we compliment girls, the labels we use, how bystanders intervene, what comfort feels like or how we nurture friendships, each brand anchored its message in something tangible and built action around it.
For startups, the lesson is straightforward: be precise in what you’re addressing, be credible in how you show up and make your message usable. Attention is easy to grab, but relevance is harder to earn and far more valuable.