Technology

Farms today are under pressure. Fields are getting bigger, workers are harder to find and many jobs still rely on long hours of manual labor. XAG’s new P150 Max agricultural drone is designed for exactly this reality. Instead of replacing farmers, it takes over the heavy, repetitive fieldwork that slows them down, making farm operations more efficient and more precise.

The P150 Max is built around one simple idea: a single machine that can handle multiple farming tasks. Most farm drones focus only on spraying or mapping, but this one is fully modular. With a quick switch of attachments, it can spray crops, spread seeds or fertilizer, map fields or transport supplies. This flexibility helps farmers keep up with changing tasks throughout the day without needing different machines, improving both productivity and cost-efficiency.

A key challenge in agriculture is that fields are rarely smooth or predictable. Tractors can get stuck, smaller drones can’t carry much and some areas—like orchards or hilly plots—are simply hard to reach. The P150 Max fills that gap with an 80-kilogram payload and fast flight speed, letting it cover more ground per trip. Fewer takeoffs mean less downtime and more work completed before weather or daylight cuts operations short.

When it’s time to spray, the drone uses a smart spraying system that allows farmers to adjust droplet size based on the crop’s needs. This matters because precise spraying reduces waste and improves targeting. With an output of up to 46 liters per minute, the drone can serve both large open fields and dense orchards where consistent coverage is traditionally difficult.

The spreading system applies the same logic. Instead of dropping seeds or fertilizer unevenly, the vertical mechanism spreads material smoothly and resists wind drift. This ensures uniform application across irregular or hard-to-reach land—an ongoing challenge for modern farms aiming for higher yield and better resource use.

Another everyday issue for farmers is understanding and surveying the land before working on it. The P150 Max helps here with a built-in mapping tool that covers up to 20 hectares per flight and instantly converts the images into detailed maps. With AI detecting obstacles like trees or irrigation lines, the drone can plan safe and efficient autonomous routes, reducing manual planning time.

Beyond spraying and spreading, the drone can transport tools, produce and farm supplies using a sling attachment. This is particularly helpful after heavy rain, when vehicles cannot easily move across muddy or flooded fields.

Under all these functions is XAG’s upgraded flight control system, which provides centimeter-level accuracy even when network signals are weak. Integrated sensors—including 4D radar and a wide-angle camera—help the drone recognize hazards such as poles and wires. Farmers can manage all operations through the XAG One app or a handheld controller, both of which automatically generate the best route based on field shape and terrain.

Since long field days require long operating hours, the fast-charging battery system can recharge in about seven minutes using a dedicated kit. This supports continuous drone use throughout the day with minimal interruptions.

After years of testing, the XAG P150 Max is essentially an effort to make practical, scalable farm automation more accessible. By combining spraying, spreading, mapping and transport into one heavy-duty platform, it offers a way to ease labor shortages while keeping operations efficient and sustainable. Instead of focusing on one task, the drone aims to take over the time-consuming physical work so farmers can focus on decisions, planning and crop management.

PowerBank Corporation and Smartlink AI, the company behind Orbit AI, are preparing to send a very different kind of satellite into space. Their upcoming mission, scheduled for December 2025, aims to test what they call the world’s first “Orbital Cloud” — a system that moves parts of today’s digital infrastructure off the ground and into orbit. While satellites already handle GPS, TV signals and weather data, this project tries to do something bigger: turn space itself into a platform for computing, artificial intelligence (AI) and secure blockchain-based digital transactions. In essence, it marks the beginning of space-based cloud computing.

To understand why this matters, it is helpful to examine the limitations of our current systems. As AI tools grow more advanced, they require massive data centers that consume enormous amounts of electricity, especially for cooling. These facilities depend on national power grids, face regulatory constraints and are concentrated in just a few regions. Meanwhile, global connectivity still struggles with inequalities, censorship, congestion and geopolitical bottlenecks. The Orbital Cloud is meant to plug these gaps by building a computing and communication layer above Earth — a solar-powered, space-cooled network in Low Earth Orbit (LEO) that no single nation or company fully controls.

Orbit AI’s approach brings together two new systems. The first, called DeStarlink, is a decentralized satellite network designed for global internet-style connectivity and resilient communication. The second, DeStarAI, is a set of AI-focused in-orbit data centers placed directly on satellites, using space’s naturally cold environment instead of the energy-hungry cooling towers used on Earth. When these two ideas merge, the result is a floating digital layer where information can be transmitted, processed and verified without touching terrestrial infrastructure — a key shift in how AI workloads and cloud computing may be handled in the future.

PowerBank enters the picture by supplying the electricity and temperature-control technology needed to keep these satellites running. In space, sunlight is constant and uninterrupted — no clouds, no storms, no nighttime periods where panels lie idle. PowerBank plans to provide high-efficiency solar arrays and adaptive thermal systems that help the satellites manage heat in orbit. This collaboration marks a shift for PowerBank, which is expanding from traditional solar and battery projects into the realm of digital infrastructure, AI energy systems and next-generation satellite technology.

Describing the ambition behind this move, Dr. Richard Lu, CEO of PowerBank, said: “The next frontier of human innovation isn't just in space exploration, it's in building the infrastructure of tomorrow above the Earth”. He pointed to a future market that could surpass US$700 billion, driven by orbital satellites, AI computing in space, blockchain verification and solar-powered data systems. Integrating solar energy with orbital computing, he said, could help create “a globally sovereign, AI-enabled digital layer in space, which is a system that can help power finance, communications and critical infrastructure”.

Orbit AI’s Co-Founder and CEO, Gus Liu, describes their satellites as deliberately autonomous and intelligent. “Orbit AI is creating the first truly intelligent layer in orbit — satellites that compute, verify and optimize themselves autonomously”, he said, “The Orbital Cloud turns space into a platform for AI, blockchain and global connectivity. By leveraging solar-powered compute payloads and decentralized verification nodes, we are opening an entirely new, potentially US$700+ billion-dollar market opportunity — one that combines energy, data and sovereignty to reshape industries from finance to government and Web3. PowerBank's expertise in advanced solar energy systems will be significant in supporting this initiative."

This vision is not isolated. Earlier this year, Jeff Bezos echoed a similar idea at Italian Tech Week, saying: “We will be able to beat the cost of terrestrial data centres in space in the next couple of decades. These giant training clusters will be better built in space, because we have solar power there, 24/7 — no clouds, no rain, no weather.  The next step is going to be data centres and then other kinds of manufacturing.” His comments reflect a growing industry belief that space-based data centers will eventually outperform those on Earth.

The idea gains traction because the advantages are practical. Space offers free, constant solar power. It provides natural cooling, which is one of the costliest parts of running data centers on Earth. And above all, satellites in low-Earth orbit operate beyond national firewalls and political boundaries, making them more resilient to outages, censorship and conflict. For industries that rely heavily on secure connectivity and real-time data — finance, defense, AI, blockchain networks and global cloud providers — this could become an important alternative layer of infrastructure.

The upcoming Genesis-1 satellite is designed as a demonstration mission. It will test an Ethereum wallet, run a blockchain verification node and perform simple AI tasks in orbit. If the technology works as expected, Orbit AI plans to add several more satellites in 2026, expand into larger networks by 2027 and 2028 and begin full commercial operations by the decade’s end.

To build this system, Orbit AI plans to source technologies from some of the world’s most influential players: NVIDIA for AI processors, the Ethereum Foundation for blockchain tools, Galaxy Space and SparkX Satellite for satellite components, Galactic Energy for launch systems and AscendX Aerospace for advanced materials.

If successful, the Orbital Cloud could become the first step toward a world where part of humanity’s data, computing power and digital services run not in massive buildings on Earth, but in clusters of autonomous satellites illuminated by constant sunlight. For now, the journey begins with a single launch — a test satellite aiming to show that space can do far more than connect us. It may soon help power the systems that run our economies, technologies and global communication networks.

Atomathic, the company once known as Neural Propulsion Systems, is stepping into the spotlight with a bold claim: its new AI platforms can help machines “see the invisible”. With the commercial launch of AIDAR™ and AISIR™, the company says it is opening a new chapter for physical AI, AI sensing and advanced sensor technology across automotive, aviation, defense, robotics and semiconductor manufacturing.

The idea behind these platforms is simple yet ambitious. Machines gather enormous amounts of signal data, yet they still struggle to understand the faint, fast or hidden details that matter most when making decisions. Atomathic says its software closes that gap. By applying AI signal processing directly to raw physical signals, the company aims to help sensors pick up subtle patterns that traditional systems miss, enabling faster reactions and more confident autonomous system performance.

"To realize the promise of physical AI, machines must achieve greater autonomy, precision and real-time decision-making—and Atomathic is defining that future," said Dr. Behrooz Rezvani, Founder and CEO of Atomathic. "We make the invisible visible. Our technology fuses the rigor of mathematics with the power of AI to transform how sensors and machines interact with the world—unlocking capabilities once thought to be theoretical. What can be imagined mathematically can now be realized physically."

This technical shift is powered by Atomathic’s deeper mathematical framework. The core of its approach is a method called hyperdefinition technology, which uses the Atomic Norm and fast computational techniques to map sparse physical signals. In simple terms, it pulls clarity out of chaos. This enables ultra-high-resolution signal visualization in real time—something the company claims has never been achieved at this scale in real-time sensing.

AIDAR and AISIR are already being trialled and integrated across multiple sectors and they’re designed to work with a broad range of hardware. That hardware-agnostic design is poised to matter even more as industries shift toward richer, more detailed sensing. Analysts expect the automotive sensor market to surge in the coming years, with radar imaging, next-gen ADAS systems and high-precision machine perception playing increasingly central roles.

Atomathic’s technology comes from a tight-knit team with deep roots in mathematics, machine intelligence and AI research, drawing talent from institutions such as Caltech, UCLA, Stanford and the Technical University of Munich. After seven years of development, the company is ready to show its progress publicly, starting with demonstrations at CES 2026 in Las Vegas.

Suppose the future of autonomy depends on machines perceiving the world with far greater fidelity. In that case, Atomathic is betting that the next leap forward won’t come from more hardware, but from rethinking the math behind the signal—and redefining what physical AI can do.

Bindwell, a San Francisco–based ag-tech startup using AI to design new pesticide molecules, has raised US$6 million in seed funding, co-led by General Catalyst and A Capital, with participation from SV Angel and Y Combinator founder Paul Graham. The round will help the company expand its lab in San Carlos, hire more technical talent and advance its first pesticide candidates toward validation.  

Even as pesticide use has doubled over the last 30 years, farmers still lose up to 40% of global crops to pests and disease. The core issue is resistance: pests are adapting faster than the industry can update its tools. As a result, farmers often rely on larger amounts of the same outdated chemicals, even as they deliver diminishing returns.

Meanwhile, innovation in the agrochemical sector has slowed, leaving the industry struggling to keep up with rapidly evolving pests. This is the gap Bindwell is targeting. Instead of updating old chemicals, the company uses AI to find completely new compounds designed for today’s pests and farming conditions.  

This vision is made even more striking by the people leading it. Bindwell was founded by 18-year-old Tyler Rose and 19-year-old Navvye Anand, who met at the Wolfram Summer Research Program in 2023. Both had deep ties to agriculture — Rose in China and Anand in India — witnessing up close how pest outbreaks and chemical dependence burdened farmers.  

Filling the gap in today’s pesticide pipeline, Bindwell created an AI system that can design and evaluate new molecules long before they hit the lab. It starts with Foldwell, the company’s protein-structure model, which helps map the shapes of pest proteins so scientists know where a molecule should bind. Then comes PLAPT, which can scan through every known synthesized compound in just a few hours to see which ones might actually work. For biopesticides, they use APPT, a model tuned to spot protein-to-protein interactions and shown to outperform existing tools on industry benchmarks.

Bindwell isn’t selling AI tools. Instead, the company develops the molecules itself and licenses them to major agrochemical players. Owning the full discovery process lets the team bake in safety, selectivity and environmental considerations from day one. It also allows Bindwell to plug directly into the pipelines that produce commercial pesticides — just with a fundamentally different engine powering the science.

At present, the team is now testing its first AI-generated candidates in its San Carlos lab and is in early talks with established pesticide manufacturers about potential licensing deals. For Rose and Anand, the long-term vision is simple: create pest control that works without repeating the mistakes of the last half-century. As they put it, the goal is not to escalate chemical use but to design molecules that are more precise, less harmful and resilient against resistance from the start.

Hong Kong is entering a new phase of competition as mainland platforms accelerate their expansion into the city, turning it into a frontline testing ground for Chinese companies preparing to push into global markets. With retail, logistics and food-delivery businesses all reshaped in the past year, Hong Kong has become the closest international environment where mainland firms can experiment with pricing, supply chains and customer behaviour under a familiar regulatory and cultural framework.

The shift became especially clear this week. At HKTVmall’s Vision Day on November 11, 2025, CEO Ricky Wong warned that Hong Kong’s traditional retail model is facing its toughest moment yet. He said the biggest threat is not mainland competitors like Taobao, JD.com or Pinduoduo entering Hong Kong, but the city’s longstanding dependence on physical shopping. If local retailers do not evolve, he said, they risk becoming “very easy to die of thirst in the desert”. Wong even welcomed the rise of mainland e-commerce giants, arguing that the more players enter the city, the faster consumers will shift online — a transition HKTVmall relies on for growth.  

Yet his optimism is layered over a challenging reality. HKTVmall’s own numbers reflect pressure from competition and changing consumer habits. The company reported average daily GMV of HK$22.2 million during the latest shopping festival season — up 2.8% month-on-month but still down 4.3% compared year-on-year — showing that even established online platforms are struggling to maintain momentum as mainland entrants squeeze prices and widen product selection.

The city’s food-delivery market illustrates the shift even more sharply. Deliveroo, once the fastest-growing platform in Hong Kong and at one point holding more than half of the market, officially shut down in April this year after a long decline. Its trajectory mirrored the sector’s upheaval: the company surged during the pandemic but lost ground after restrictions eased, first overtaken by Foodpanda and then pressured heavily by Meituan-backed Keeta, which entered Hong Kong in 2023 and quickly seized about 30% of citywide orders.

Deliveroo’s exit and the handover of parts of its business to Foodpanda did little to stabilise the market. Keeta’s rapid expansion instead pushed Foodpanda onto the defensive, leaving two major players competing in a market shaped by mainland-style pricing and operations. Hong Kong’s delivery sector, once dominated by global firms, is increasingly defined by Chinese platforms optimizing speed and efficiency at a scale few competitors can match.

These changes are unfolding as Chinese companies shift their focus toward new global markets.  

With China reducing its reliance on the US and EU and exports steadily moving toward ASEAN, Hong Kong has become a strategic launchpad. The city’s proximity, language familiarity and regulatory structure make it the nearest international setting where Chinese firms can test overseas strategies before expanding into Southeast Asia, the Middle East or Latin America. The result is a competitive intensity that local companies have rarely experienced. Retailers face price pressure they can’t match, local platforms are losing ground to mainland giants and global players are struggling to stay in the game.

Consumers benefit from lower prices, faster delivery and wider choice — but for Hong Kong businesses, the landscape has turned unforgiving. Mainland companies are not treating Hong Kong as a final destination but as the first stop in a broader global push. That positioning is reshaping the city’s entire consumer economy. As more mainland firms look outward, Hong Kong’s role as a testing ground will only deepen and the first players to feel the impact will be those operating closest to the consumer.

In a world where digital borders are fading faster than ever, Tencent is betting on familiarity. With the launch of TenPay Global Checkout, the company wants to make paying across countries feel as seamless as paying at home.

The new service, unveiled today, allows Weixin Mini Program merchants outside mainland China to accept a variety of local payment methods. That includes digital wallets, real-time payment networks and credit and debit cards, all through a single integration. The launch starts in Singapore and Macao SAR, where merchants can now take payments via PayNow, BOCPAY(MO), and major cards. Japan, Australia and New Zealand are next, with more regions to follow soon.

This rollout builds on the growing reach of Weixin Mini Programs, known internationally through WeChat. These small apps are built right into the platform, letting users' shop, book services and make payments without downloading separate apps. Today, there are over one million monthly active users in key overseas markets, with Mini Programs available across 92 countries and regions.  

Yet, for many users abroad, paying within Mini Programs hasn’t always been simple. Foreign card restrictions, currency conversions and limited local options often made checkout a frustrating step. TenPay Global Checkout aims to change that.

“TenPay Global Checkout marks an important step in enhancing the local consumer experience. By enabling overseas Weixin Mini Program merchants to accept trusted and diversified local payment methods through one unified solution, users benefit from a more convenient and efficient payment experience.  This helps merchants improve payment conversion rates, expand their user base and scale their businesses to serve a broader range of customers”, said Wenhui Yang, CEO of TenPay Global (Singapore).

What makes this move interesting isn’t just its technical simplicity—it’s the cultural bridge it builds. For users in Singapore or Japan, paying with PayNow or a local card inside Weixin feels less like an international transaction and more like an everyday purchase.

For merchants, it’s an invitation into a market that values convenience and trust. Payment familiarity, after all, often decides whether a user completes a purchase or abandons it at checkout.

The company remains focused on creating secure, connected and user-friendly payment experiences that help merchants grow and allow consumers to pay with confidence, wherever they are.  

If successful, TenPay Global Checkout could quietly redefine how cross-border commerce feels—not like a transaction across regions, but a familiar tap, scan or click. In an increasingly global marketplace, that kind of familiarity might just be the next frontier in digital trust.

It’s no surprise that artificial intelligence, while remarkably capable, can also go astray—spinning convincing but entirely fabricated narratives. From politics to academia, AI’s “hallucinations” have repeatedly shown how powerful technology can go off-script when left unchecked.

Take Grok-2, for instance. In July 2024, the chatbot misled users about ballot deadlines in several U.S. states, just days after President Joe Biden dropped his re-election bid against former President Donald Trump. A year earlier, a U.S. lawyer found himself in court for relying on ChatGPT to draft a legal brief—only to discover that the AI tool had invented entire cases, citations and judicial opinions. And now, the academic world has its own cautionary tale.

Recently, a journal paper from the Department of Social Work and Social Administration at the University of Hong Kong was found to contain fabricated citations—sources apparently created by AI. The paper, titled “Forty Years of Fertility Transition in Hong Kong,” analyzed the decline in Hong Kong’s fertility rate over the past four decades. Authored by doctoral student Yiming Bai, along with Yip Siu-fai, Vice Dean of the Faculty of Social Sciences and other university officials, the study identified falling marriage rates as a key driver behind the city’s shrinking birth rate. The authors recommended structural reforms to make Hong Kong’s social and work environment more family-friendly.

But the credibility of the paper came into question when inconsistencies surfaced among its references. Out of 61 cited works, some included DOI (Digital Object Identifier) links that led to dead ends, displaying “DOI Not Found.” Others claimed to originate from academic journals, yet searches yielded no such publications.

Speaking to HK01, Yip acknowledged that his student had used AI tools to organize the citations but failed to verify the accuracy of the generated references. “As the corresponding author, I bear responsibility”, Yip said, apologizing for the damage caused to the University of Hong Kong and the journal’s reputation. He clarified that the paper itself had undergone two rounds of verification and that its content was not fabricated—only the citations had been mishandled.

Yip has since contacted the journal’s editor, who accepted his explanation and agreed to re-upload a corrected version in the coming days. A formal notice addressing the issue will also be released. Yip said he would personally review each citation “piece by piece” to ensure no errors remain.

As for the student involved, Yip described her as a diligent and high-performing researcher who made an honest mistake in her first attempt at using AI for academic assistance. Rather than penalize her, Yip chose a more constructive approach, urging her to take a course on how to use AI tools responsibly in academic research.

Ultimately, in an age where generative AI can produce everything from essays to legal arguments, there are two lessons to take away from this episode. First, AI is a powerful assistant, but only that. The final judgment must always rest with us. No matter how seamless the output seems, cross-checking and verifying information remain essential. Second, as AI becomes integral to academic and professional life, institutions must equip students and employees with the skills to use it responsibly. Training and mentorship are no longer optional; they’re the foundation for using AI to enhance, not undermine, human work.

Because in this age of intelligent machines, staying relevant isn’t about replacing human judgment with AI, it’s about learning how to work alongside it.

Neuron7.ai, a company that builds AI systems to help service teams resolve technical issues faster, has launched Neuro. It is a new kind of AI agent built for environments where accuracy matters more than speed. From manufacturing floors to hospital equipment rooms, Neuro is designed for situations where a wrong answer can halt operations.

What sets Neuro apart is its focus on reliability. Instead of relying solely on large language models that often produce confident but inaccurate responses, Neuro combines deterministic AI — which draws on verified, trusted data — with autonomous reasoning for more complex cases. This hybrid design helps the system provide context-aware resolutions without inventing answers or “hallucinating”, a common issue that has made many enterprises cautious about adopting agentic AI.

“Enterprise adoption of agentic AI has stalled despite massive vendor investment. Gartner predicts 40% of projects will be canceled by 2027 due to reliability concerns”, said Niken Patel, CEO and Co-Founder of Neuron7. “The root cause is hallucinations. In service operations, outcomes are binary. An issue is either resolved or it is not. Probabilistic AI that is right only 70% of the time fails 30% of your customers and that failure rate is unacceptable for mission-critical service”.

That concern shaped how Neuro was built. “We use deterministic guided fixes for known issues. No guessing, no hallucinations — and reserve autonomous AI reasoning for complex scenarios. What sets Neuro apart is knowing which mode to use. While competitors race to make agents more autonomous, we're focused on making service resolution more accurate and trusted”, Patel explained.

At the heart of Neuro is the Smart Resolution Hub, Neuron7’s central intelligence layer that consolidates service data, knowledge bases and troubleshooting workflows into one conversational experience. This means a technician can describe a problem — say, a diagnostic error in an MRI scanner — and Neuro can instantly generate a verified, step-by-step solution. If the problem hasn’t been encountered before, it can autonomously scan through thousands of internal and external data points to identify the most likely fix, all while maintaining traceability and compliance.

Neuro’s architecture also makes it practical for real-world use. It integrates seamlessly with enterprise systems such as Salesforce, Microsoft, ServiceNow and SAP, allowing companies to embed it within their existing support operations. Early users of Neuron7’s platform have reported measurable improvements — faster resolutions, higher customer satisfaction and reduced downtime — thanks to guided intelligence that scales expert-level problem solving across teams.

The timing of Neuro’s debut feels deliberate. As organizations look to move past the hype of generative AI, trust and accountability have become the new benchmarks. AI systems that can explain their reasoning and stay within verifiable boundaries are emerging as the next phase of enterprise adoption.

“The market has figured out how to build autonomous agents”, Patel said. “The unsolved problem is building accurate agents for contexts where errors have consequences. Neuro fills that gap”.

Neuron7 is building a system that knows its limits — one that reasons carefully, acts responsibly and earns trust where it matters most. In a space dominated by speculation, that discipline may well redefine what “intelligent” really means in enterprise AI.

Encyclopaedias have always been mirrors of their time — from heavy leather-bound volumes in the 19th century to Wikipedia’s community-edited pages online. But as the world’s information multiplies faster than humans can catalogue it, even open platforms struggle to keep pace. Enter Botipedia, a new project from INSEAD, The Business School for the World, that reimagines how knowledge can be created, verified and shared using artificial intelligence.

At its core, Botipedia is powered by proprietary AI that automates the process of writing encyclopaedia entries. Instead of relying on volunteers or editors, it uses a system called Dynamic Multi-method Generation (DMG) — a method that combines hundreds of algorithms and curated datasets to produce high-quality, verifiable content. This AI doesn’t just summarise what already exists; it synthesises information from archives, satellite feeds and data libraries to generate original text grounded in facts.

What makes this innovation significant is the gap it fills in global access to knowledge. While Wikipedia hosts roughly 64 million English-language entries, languages like Swahili have fewer than 40,000 articles — leaving most of the world’s population outside the circle of easily available online information. Botipedia aims to close that gap by generating over 400 billion entries across 100 languages, ensuring that no subject, event or region is overlooked.

"We are creating Botipedia to provide everyone with equal access to information, with no language left behind", says Phil Parker, INSEAD Chaired Professor of Management Science, creator of Botipedia and holder of one of the pioneering patents in the field of generative AI. "We focus on content grounded in data and sources with full provenance, allowing the user to see as many perspectives as possible, as opposed to one potentially biased source".

Unlike many generative AI tools that depend on large language models (LLMs), Botipedia adapts its methods based on the type of content. For instance, weather data is generated using geo-spatial techniques to cover every possible coordinate on Earth. This targeted, multi-method approach helps boost both the accuracy and reliability of what it produces — key challenges in today’s AI-driven content landscape.

Additionally, the innovation is also energy-efficient. Its DMG system operates at a fraction of the processing power required by GPU-heavy models like ChatGPT, making it a sustainable alternative for large-scale content generation.

By combining AI precision, linguistic inclusivity and academic credibility, Botipedia positions itself as more than a digital library — it’s a step toward universal, unbiased access to verified knowledge.

"Botipedia is one of many initiatives of the Human and Machine Intelligence Institute (HUMII) that we are establishing at INSEAD", says Lily Fang, Dean of Research and Innovation at INSEAD. "It is a practical application that builds on INSEAD-linked IP to help people make better decisions with knowledge powered by technology. We want technologies that enhance the quality and meaning of our work and life, to retain human agency and value in the age of intelligence".

By harnessing AI to bridge gaps of language, geography and credibility, Botipedia points to a future where access to knowledge is no longer a privilege, but a shared global resource.

Artificial intelligence is beginning to change how scientists understand cancer at the cellular level. In a new collaboration, Bio-Techne Corporation, a global life sciences tools provider, and Nucleai, an AI company specializing in spatial biology for precision medicine, have unveiled data from the SECOMBIT clinical trial that could reshape how doctors predict cancer treatment outcomes. The results, presented at the Society for Immunotherapy of Cancer (SITC) 2025 Annual Meeting, highlight how AI-powered analysis of tumor environments can reveal which patients are more likely to benefit from specific therapies.

Led in collaboration with Professor Paolo Ascierto of the University of Napoli Federico II and Istituto Nazionale Tumori IRCCS Fondazione Pascale, the study explores how spatial biology — the science of mapping where and how cells interact within tissue — can uncover subtle immune behaviors linked to survival in melanoma patients.

Using Bio-Techne’s COMET platform and a 28-plex multiplex immunofluorescence panel, researchers analyzed 42 pre-treatment biopsies from patients with metastatic melanoma, an advanced stage of skin cancer. Nucleai’s multimodal AI platform integrated these imaging results with pathology and clinical data to trace patterns of immune cell interactions inside tumors.

The findings revealed that therapy sequencing significantly influences immune activity and patient outcomes. Patients who received targeted therapy followed by immunotherapy showed stronger immune activation, marked by higher levels of PD-L1+ CD8 T-cells and ICOS+ CD4 T-cells. Those who began with immunotherapy benefited most when PD-1+ CD8 T-cells engaged closely with PD-L1+ CD4 T-cells along the tumor’s invasive edge. Meanwhile, in patients alternating between targeted and immune treatments, beneficial antigen-presenting cell (APC) and T-cell interactions appeared near tumor margins, whereas macrophage activity in the outer tumor environment pointed to poorer prognosis.

“This study exemplifies how our innovative spatial imaging and analysis workflow can be applied broadly to clinical research to ultimately transform clinical decision-making in immuno-oncology”, said Matt McManus, President of the Diagnostics and Spatial Biology Segment at Bio-Techne.

The collaboration between the two companies underscores how AI and high-plex imaging together can help decode complex biological systems. As Avi Veidman, CEO of Nucleai, explained, “Our multimodal spatial operating system enables integration of high-plex imaging, data and clinical information to identify predictive biomarkers in clinical settings. This collaboration shows how precision medicine products can become more accurate, explainable and differentiated when powered by high-plex spatial proteomics – not limited by low-plex or H&E data alone”.

Dr. Ascierto described the SECOMBIT trial as “a milestone in demonstrating the possible predictive power of spatial biomarkers in patients enrolled in a clinical study”.

The study’s broader message is clear: understanding where immune cells are and how they interact inside a tumor could become just as important as knowing what they are. As AI continues to map these microscopic landscapes, oncology may move closer to genuinely personalized treatment — one patient, and one immune network, at a time.